Smash Mol cula is a card game in which chemical elements battle for supremacy. Each player holds three element cards at the beginning of a turn. Each element has a special power when you play it, such as drawing more cards or stealing cards from others. The cards have positive or negative values, and if you can play several cards with a sum of 0, you can draw a molecule card that will score points. Molecules, however, can also react to other molecules, so that your points aren't safe. The first player to reach 10 points wins the game.

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