In Ca a ao Mosquito da Dengue players are trying to prevent Dengue fever from spreading by finding nests of mosquitos on opponent's headquarter. Each round, on the player's turn, he guesses where the nest could be at the other's grid by saying a combination of color and number, if you miss, the opponent marks the area with "X", and pass his turn. If guess is correct he marks the combination on his grid to complete the object (rail, vessel, tire, water tank or bottle) receiving the correspondent card. Victory goes to the player who collect 5 different kind of cards first, and the others continue to set the 2nd and 3rd places.

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